CALON'S HISTORY BODES WELL FOR A POSITIVE FUTURE

What is the challenge?

In 2007, Prof Stephen Westaby, an eminent heart surgeon and pioneer of mechanical circulatory support and Prof Marc Clement, a chartered engineer, chartered physicist and serial entrepreneur met and founded Calon Cardio-Technology Ltd. They set off with a mission to develop an Implantable Heart Pump that is best-in-class.

Blood is a very delicate fluid and the application of a mechanical pumping action exposes the blood to potential damage. Damage can originate from the action of moving parts, contact with certain materials, non-uniform flow or by heat generated by the device. While the benefits of the pumps currently approved for implant outweigh their drawbacks, Calon has applied Computational Fluid Dynamics, Multi-Physics Analysis, Materials Science and design and engineering to develop the Calon MiniVAD™. Pre-clinical testing supports the outcomes of the modelling in terms of improved blood handling compared with the heart pumps currently on the market.

Based on the clinical experience of leading cardiac surgeon Professor Stephen Westaby, Calon established itself in Swansea under the guidance of Professor Marc Clement in 2007.

Calon has assembled a first class team with world leading expertise in the areas required to deliver the next generation implantable blood pump and associated control system.

Meet the Team >

The solution

Extensive computer modelling, design, engineering and testing (both in vitro and pre-clinical in vivo studies) have demonstrated the Calon MiniVAD™'s potential for reducing blood damage significantly when compared with market released pumps. This improved blood handling is expected to correspond to a reduction in the incidence of adverse events such as stroke, internal bleeding and damage to other organs.

The Technical Team is preparing the MiniVAD™ to be ready for human clinical studies in the UK / Europe and an Early Feasibility Study in the USA.

All Calon's development and testing is carried out in the offices and laboratories of the new purpose-built, pilot production facility in Swansea, Wales.

TEAM

Executive Team and Board

Prof. Stephen Westaby

DIRECTOR & FOUNDER

Steve is recognised as one of the world’s most innovative cardiac surgeons. He is a former Consultant Cardiac Surgeon at John Radcliffe Hospital, Oxford and he continues to pioneer combined pump and stem cell therapies. At Oxford in 2000, Prof Westaby implanted the first permanent LVAD into a human patient. Following his recent retirement from surgery, Steve has become a published author of books including “Fragile Lives” (titled “Open Heart” in N America) and “The Knife’s Edge”.

Ron Petersen

INVESTOR DIRECTOR

Ron is Co-founder of Longbow Capital LLP and was formerly the Managing Director at the Boots Centre for Innovation. Ron has more than 20 years’ experience with Armstrong World Industries, managing global businesses, focusing on turning underperforming or early stage companies into profitable and valued concerns. Ron has been directly involved in the founding of a number of technology companies, particularly in the nanotechnology field.

Prof. Marc Clement

CHAIRMAN & FOUNDER

Marc is a serial entrepreneur. He has worked in the field of medical devices for many years, specialising in the development and commercialisation of novel light-based technologies for clinical applications. He has extensive experience of the regulatory process necessary for the introduction of medical devices.

Andrew Goodwin

INVESTOR DIRECTOR

Andrew revolutionised the utilities market in Germany when in 1998 he founded Verivox, Germany’s first and largest independent consumer energy portal. He is a serial investor and advises and invests in early stage businesses.